| Item Type | Name |
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Concept
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Gene Expression Regulation
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Concept
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Up-Regulation
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Concept
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Down-Regulation
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Concept
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Gene Expression Regulation, Viral
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Concept
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Gene Expression Regulation, Enzymologic
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Concept
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Gene Expression Regulation, Leukemic
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Concept
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Gene Expression Regulation, Neoplastic
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Academic Article
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Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.
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Academic Article
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Ionizing radiation down-regulates histone H1 gene expression by transcriptional and post-transcriptional mechanisms.
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Academic Article
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Phorbol ester-induced monocytic differentiation is associated with G2 delay and down-regulation of cdc25 expression.
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Academic Article
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Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
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Academic Article
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Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis.
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Academic Article
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Tumor necrosis factor alpha (TNF-alpha) gene therapy targeted by ionizing radiation selectively damages tumor vasculature.
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Academic Article
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Down-regulation of cell cycle control genes by ionizing radiation.
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Academic Article
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Differentiation and retrodifferentiation of human myeloid leukemia cells is associated with reversible induction of cell cycle-regulatory genes.
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Academic Article
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Involvement of reactive oxygen intermediates in the induction of c-jun gene transcription by ionizing radiation.
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Academic Article
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Inhibition of protein kinases sensitizes human tumor cells to ionizing radiation.
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Academic Article
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Radiogenetic therapy: on the interaction of viral therapy and ionizing radiation for improving local control of tumors.
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Academic Article
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Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase.
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Academic Article
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Regulation of Rad51 function by c-Abl in response to DNA damage.
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Academic Article
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Thymidylate synthase expression and response to neoadjuvant chemotherapy in patients with advanced head and neck cancer.
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Academic Article
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Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors.
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Academic Article
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Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.
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Academic Article
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Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90.
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Academic Article
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Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase.
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Academic Article
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Radiation-inducible gene therapy.
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Academic Article
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Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis.
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Academic Article
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Quantitative analysis of DNA array autoradiographs.
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Academic Article
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TNFerade Biologic: preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene.
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Academic Article
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Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine.
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Academic Article
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Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma.
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Academic Article
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Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
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Academic Article
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Evidence for the expression of radiation-induced potentially lethal damage being a p53-dependent process.
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Academic Article
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The role of cdc2 in the expression of herpes simplex virus genes.
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Academic Article
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Inhibition of glioma cell growth and tumorigenic potential by CCN3 (NOV).
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Academic Article
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The novel isocoumarin 2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl) propionic acid (NM-3) induces lethality of human carcinoma cells by generation of reactive oxygen species.
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Academic Article
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Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.
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Academic Article
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Lyn tyrosine kinase inhibits nuclear export of the p53 tumor suppressor.
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Academic Article
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Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation.
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Academic Article
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Control of gene therapy by MDR1 and EGR1 promoter sequences in transcriptional targeting by chemotherapy (Review).
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Academic Article
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Radiation-induced tumour necrosis factor-alpha expression: clinical application of transcriptional and physical targeting of gene therapy.
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Academic Article
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Radiation therapy: activation for gene transcription and the development of genetic radiotherapy-therapeutic strategies in oncology.
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Academic Article
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Mechanisms of X-ray-mediated protooncogene c-jun expression in radiation-induced human sarcoma cell lines.
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Academic Article
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Possible applications of biotechnology to radiotherapy.
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Academic Article
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Biological consequences of gene regulation after ionizing radiation exposure.
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Academic Article
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Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity.
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Academic Article
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Ionizing radiation: a genetic switch for cancer therapy.
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Academic Article
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Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.
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Academic Article
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Ionizing radiation regulates expression of the c-jun protooncogene.
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Academic Article
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TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors.
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Academic Article
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MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer.
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Academic Article
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Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma.
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Academic Article
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Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling.
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Academic Article
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MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients.
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Academic Article
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Simvastatin attenuates radiation-induced murine lung injury and dysregulated lung gene expression.
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Academic Article
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Vascular endothelial growth factor pathway.
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Academic Article
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STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect.
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Academic Article
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Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.
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Academic Article
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Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression.
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Academic Article
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Some retinoblastomas, osteosarcomas, and soft tissue sarcomas may share a common etiology.
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Academic Article
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Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs.
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Academic Article
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Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner.
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Academic Article
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Membrane-derived second messenger regulates x-ray-mediated tumor necrosis factor alpha gene induction.
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Academic Article
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Ionizing radiation activates transcription of the EGR1 gene via CArG elements.
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Academic Article
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Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy.
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Academic Article
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Spatial and temporal control of gene therapy using ionizing radiation.
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Academic Article
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Ketoconazole attenuates radiation-induction of tumor necrosis factor.
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Academic Article
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Radiation induction of immediate early genes: effectors of the radiation-stress response.
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Academic Article
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Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer.
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Academic Article
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Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells.
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Academic Article
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Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase.
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Academic Article
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Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide.
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Academic Article
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Molecular targets to overcome radioresistance.
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Academic Article
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Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1.
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Academic Article
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Glioblastoma cells block radiation-induced programmed cell death of endothelial cells.
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Academic Article
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Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes.
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Academic Article
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Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis.
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Academic Article
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MicroRNA expression characterizes oligometastasis(es).
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Academic Article
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DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site.
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Academic Article
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Cholesterol metabolism and resistance to tamoxifen.
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Academic Article
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Role of migratory inhibition factor in age-related susceptibility to radiation lung injury via NF-E2-related factor-2 and antioxidant regulation.
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Academic Article
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Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor.
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Academic Article
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DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy.
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Academic Article
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Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide.
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Academic Article
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MUC1-C activates the TAK1 inflammatory pathway in colon cancer.
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Academic Article
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Very low doses of ionizing radiation and redox associated modifiers affect survivin-associated changes in radiation sensitivity.
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Academic Article
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Basal Tumor Cell Isolation and Patient-Derived Xenograft Engraftment Identify High-Risk Clinical Bladder Cancers.
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Academic Article
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Combination of radiotherapy and vaccination overcomes checkpoint blockade resistance.
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Academic Article
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Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma.
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Academic Article
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CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response.
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Academic Article
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Low Recombination Proficiency Score (RPS) Predicts Heightened Sensitivity to DNA-Damaging Chemotherapy in Breast Cancer.
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Academic Article
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In Vivo Delivery and Therapeutic Effects of a MicroRNA on Colorectal Liver Metastases.
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Academic Article
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STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability.
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Academic Article
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BCL3 expression promotes resistance to alkylating chemotherapy in gliomas.
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Academic Article
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A Critical Role of the IL-1ß-IL-1R Signaling Pathway in Skin Inflammation and Psoriasis Pathogenesis.
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Academic Article
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ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response.
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Academic Article
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TP53 Mutational Status and ROS Effect the Expression of the Survivin-Associated Radio-Adaptive Response.
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Academic Article
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Rhythmic radiotherapy beats down TGF-ß.
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Academic Article
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DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs.
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Academic Article
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Molecular Classification of Lymph Node Metastases Subtypes Predict for Survival in Head and Neck Cancer.
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Academic Article
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RIG-I-Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy.
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Academic Article
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The Change of Soluble Programmed Cell Death-Ligand 1 in Glioma Patients Receiving Radiotherapy and Its Impact on Clinical Outcomes.
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Academic Article
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CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma.
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Academic Article
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The relationship between expression of PD-L1 and HIF-1a in glioma cells under hypoxia.
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Academic Article
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Oligometastases: Characterizing the Role of Epigenetic Regulation of Epithelial-Mesenchymal Transition.
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Academic Article
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YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.
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Academic Article
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Epitranscriptional regulation of TGF-ß pseudoreceptor BAMBI by m6A/YTHDF2 drives extrinsic radioresistance.
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